Tomas Majtan Selected Research

Homocystinuria

9/2020	Interplay of Enzyme Therapy and Dietary Management of Murine Homocystinuria.
6/2020	Classical homocystinuria: From cystathionine beta-synthase deficiency to novel enzyme therapies.
1/2020	Long-term uninterrupted enzyme replacement therapy prevents liver disease in murine model of severe homocystinuria.
11/2019	Behavior, body composition, and vascular phenotype of homocystinuric mice on methionine-restricted diet or enzyme replacement therapy.
5/2018	Pharmacokinetics and pharmacodynamics of PEGylated truncated human cystathionine beta-synthase for treatment of homocystinuria.
1/2018	Enzyme replacement therapy prevents loss of bone and fat mass in murine homocystinuria.
1/2018	Crystal structure of cystathionine β-synthase from honeybee Apis mellifera.
1/2018	Potential Pharmacological Chaperones for Cystathionine Beta-Synthase-Deficient Homocystinuria.
1/2018	Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria.
12/2017	Enzyme replacement prevents neonatal death, liver damage, and osteoporosis in murine homocystinuria.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Tomas Majtan Research Topics

Disease

21	Homocystinuria 09/2020 - 05/2010
2	Hypermethioninemia 09/2020 - 01/2020
2	Hyperhomocysteinemia 09/2020 - 01/2020
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2013 - 05/2010
1	Down Syndrome (Down's Syndrome) 01/2022
1	Stroke (Strokes) 01/2020
1	Liver Diseases (Liver Disease) 01/2020
1	Thrombosis (Thrombus) 01/2020
1	Vascular Diseases (Vascular Disease) 01/2020
1	Hemorrhage 01/2020
1	Propionic Acidemia 01/2018
1	Osteoporosis 12/2017
1	Perinatal Death 12/2017
1	Metabolic Diseases (Metabolic Disease) 01/2016
1	Wounds and Injuries (Trauma) 09/2013
1	Inflammation (Inflammations) 09/2013

Drug/Important Bio-Agent (IBA)

8	Cystathionine beta-Synthase (Serine Sulfhydrase)IBA 06/2020 - 05/2010
8	HomocysteineIBA 01/2020 - 09/2014
7	Sulfur Amino AcidsIBA 01/2018 - 11/2012
6	CystathionineIBA 01/2022 - 12/2012
4	Proteins (Proteins, Gene)FDA Link 09/2020 - 04/2012
4	EnzymesIBA 06/2020 - 01/2016
3	Methionine (L-Methionine)FDA Link 09/2020 - 01/2016
3	Cysteine (L-Cysteine)FDA Link 12/2017 - 01/2016
2	SulfurIBA 06/2020 - 10/2013
2	S-Adenosylmethionine (Ademetionine)IBA 01/2018 - 07/2016
2	LigandsIBA 01/2016 - 01/2013
1	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 01/2022
1	Betaine (C.B.B.)FDA Link 09/2020
1	Propionyl-Coenzyme A Carboxylase (Propionyl CoA Carboxylase)IBA 01/2018
1	FlavonoidsIBA 09/2013
1	Peptide Hydrolases (Proteases)FDA Link 09/2013
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 09/2013
1	Pyridoxine (Pyridoxin)FDA LinkGeneric 05/2010

Therapy/Procedure

6	Enzyme Replacement Therapy 01/2020 - 01/2016
3	Enzyme Therapy 09/2020 - 01/2020
2	Therapeutics 01/2020 - 07/2016